Scientific Associate
AUTO/TRANS/INFL - NIBR
Basel, Switzerland
vor 6 Tg.

Position Purpose :

We are looking for a highly motivated and committed scientist to join our immunology research team within the Autoimmunity, Transplantation & Inflammation Disease Area.

Your responsibilities will be to :

  • Interact with cross-functional and cross-divisional project teams active in drug development
  • Work with cell cultures, primary immune cells and human tissue for drug development and target validation
  • Establish state of the art molecular and cellular technology to build mechanistic assays and to investigate the function of primary human immune cells
  • Master a wide range of methods, like WB, ELISA, CRISPR / Cas9, multicolor flow cytometry and the assessment of in vitro leukocyte differentiation for the characterization of novel immuno-
  • modulating substances and pathways

  • You will work in a lab team, in a science-driven environment with both exploratory and operational functions
  • You can expect to contribute to the investigations and understanding of novel pathways in human immunology and to apply cellular systems for drug discovery and optimization
  • Minimum requirements

  • MSc, BSc, Diploma or strong apprenticeship in immunology and cell biology
  • Solid knowledge and practical experience of cell culture methods including primary human and murine cells is a must
  • Expertise in analysis of large datasets (multi-parameter cytometry, NGS methods), background in cellular biology, molecular biology and immunology are positive assets
  • Experienced with a variety of in vitro cell biology methods (e.g. flow cytometry, qPCR, digital PCR, NGS, single cell analysis and western blot)
  • Experience in isolating, handling and stimulating primary human leukocytes is preferred
  • Theoretical knowledge of immunology and immunological methods is an advantage
  • Reliable, meticulous and high performant lab operating skills
  • Eager to learn new technologies and to perform exploratory activities
  • Strong ability to both work independently and as a team member
  • Scientific curiosity, initiative, commitment, flexibility and good organization skills
  • Good balance between analytical careful thinking and a practical / pragmatic approach
  • Excellent English language skills; knowledge of German is advantageous
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