Postdoctoral Fellow - primary blood cell genome editing and engineering
Genome Biology (Corn Lab)
Zurich
vor 1 Tg.
source : ETH Zürich

Job description

We are looking for a full-time postdoc (100%) interested in genome editing and engineering of primary blood cells. These approaches will be used to ask fundamental questions about cell biology and to design new therapeutic strategies.

Hematopoietic stem cells are one focus of the lab, but other primary blood cell types are also of interest. The candidate will work on new methods to track cell identity and state via sequence-based barcoding, modify endogenous sequences to cure genetic disorders, and link genotype with phenotype via single cell technologies.

You will have access to state-of-the-art facilities, outstanding colleagues, and freedom to develop your own independent research focus as you transition to an independent career.

Required Experience

  • Ph.D. in molecular and cell biology, genomics, molecular medicine, or a related discipline
  • Human cell culture (immortalized or primary cells)
  • Next-generation sequencing for functional genomics (e.g. one or more of RNA-seq, ChIP-seq, ATAC-seq, CRISPR libraries, etc)
  • At least one peer-reviewed, first-author publication
  • Collaborative and curious mindset
  • Proficiency in speaking and writing English
  • Preferred Experience

  • Single-cell sequencing technologies
  • BSL2 viral work (lentivirus and / or adenoassociated virus)
  • Mouse work
  • Some familiarity with bioinformatics analysis (e.g. pipelines for seq)
  • Women and underrepresented minorities are particularly encouraged to apply.

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