Senior/Principal Scientist& Mass Spectrometry Proteomics
Ridgeline Discovery GmbH
Basel, Basel City, Switzerland
vor 6 Tg.

Ridgeline Discovery is looking for a Senior / Principal Scientist, Mass Spectrometry Proteomics .

Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe.

In recent years, Ridgeline has assembled an international team of >

50 highly experienced drug discovery professionals and built and operated several new successful companies, including Black Diamond Therapeutics (NASDAQ : BDTX), Bright Peak Therapeutics and Monte Rosa Therapeutics (NASDAQ : GLUE).

Ridgeline is currently expanding its capabilities in Basel to support further company creation efforts in small molecules, biologics, and gene / cell therapy with focus on oncology and immunology.

We are looking for a highly motivated Scientist with strong experience in mass spectrometry-based proteomics for supporting innovative drug discovery.

The candidate will be responsible for independently conducting his / her own proteomics experiments from sample preparation, LC-MS / MS, to data analysis, interpretation, and presentation of the results.

We are looking for a candidate with excellent technical and organizational skills, and a strong collaborative spirit.


You will further strengthen our team by contributing to the development of new biotech companies. You will help increase the biological understanding of programs as well as developing novel analytical assays to help moving our companies forward.

Your role will be comprised of :

  • Developing and validating proteomic analytical assays with the use of LC-MS / MS Thermo mass spectrometer and bioinformatics software
  • Performing qualitative and quantitative mass spectrometry analysis including biological sample preparation
  • Working independently to develop MS methods, designing, and executing advanced experiments, analyzing, interpreting, and presenting the data to the team
  • Keeping abreast of current literature on cutting edge techniques in the field of proteomics
  • Suggesting experimental approaches to support the needs of Ridgeline companies for proteomics
  • Working with Data Science group to build cutting edge bioinformatic and deep learning tools
  • Presenting to leadership team and board members for Ridgeline Discovery companies
  • Preparing and maintaining the proteomics core of Ridgeline

  • PhD in Biology, Biochemistry, or related field
  • 5+ years experience in proteomics in Pharma, Biotech or equivalent
  • Experience in proteomics, peptide mapping, intact protein mass, PTMs modifications is a must
  • Critical and independent thinking
  • Strong analytical and problem-solving skills
  • Strong scientific curiosity and interest in drug discovery
  • Well-organized, highly motivated, and quick to learn
  • Highly collaborative and able to work in a matrix-type, interactive, and fast-paced drug discovery environment
  • Excellent oral and written communication skills
  • To apply, please send us the application form together with your CV and Cover Lett er .

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