Scientist CMC Process Development – Cell Therapy
Ridgeline Discovery GmbH
Basel, Basel City, Switzerland
vor 4 Tg.

Ridgeline Discovery is looking for a Scientist CMC Process Development Cell Therapy .

Ridgeline Discovery, a Versant Ventures Discovery Engine creates and operates Versant-financed innovative biotech companies in Basel, Switzerland.

In recent years, Ridgeline has assembled an international team of >

35 highly experienced drug discovery professionals and built and operated several new successful companies, including Black Diamond Therapeutics (Nasdaq : BDTX), Bright Peak Therapeutics and Monte Rosa Therapeutics.

Ridgeline is currently expanding its capabilities in Basel to support further company creation efforts in small molecules, biologics, and gene / cell therapy with focus on oncology and immunology.

This Basel (Switzerland) based position offers a tremendous opportunity to support our growing companies in an experienced, vibrant and agile biotech team.

The successful candidate will be highly motivated and enthusiastic with a positive can-do attitude, hands-on, strong analytical and organizational skills and strategic mindset.


  • Participate in the development of a GMP-compliant manufacturing process and control strategy for cell-based products (genetically engineered T-based and / or hematopoietic stem cell-based products)
  • Support design of studies and execute experiments needed to establish consistent manufacturing processes and analytic procedures for cellular products
  • Support evaluation and implementation of technologies and materials required for successful manufacturing cell therapy products
  • Participate in process characterization studies
  • Collaborate with research, analytical development, and external partners to design, develop and implement a GMP-compliant cell therapy manufacturing process
  • Review and / or assist in writing and revising technical documents including laboratory SOPs, protocols and reports

  • MS degree in bioengineering or life science or similar
  • Direct experience (2+ years) with manufacturing process development for mammalian cells or preferable primary cell cultures in a cell and gene therapy environment
  • Expertise with various cell culture platforms (e.g. cell culture bags, G-Rex and / or Cell culture stacks) and devices used in the manufacturing for cellular products (e.
  • g. CliniMACS Prodigy, CliniMACS plus, Sepax, and / or Lovo, etc.) would be desirable

  • Working knowledge with regard to the application of DoE approaches would be desirable
  • Experience with the cultivation of human cells is required, preferably primary T cells and / or hematopoietic stem cells
  • Experience within a GMP-regulated environment would be of advantage
  • Ability to work independently and to participate in cross-functional teams, meet deadlines, and organize and prioritize work
  • Self-organizer, keen attention to detail
  • Ability to acquire knowledge quickly in the rapidly expanding adoptive cell therapy field
  • Excellent communication skills with ability to communicate across a variety of audiences including team members and cross-functional project teams
  • To apply , please send us this application form together with your CV and Cover Letter .

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