Ridgeline Discovery is looking for a Scientist CMC Process Development Cell Therapy .
Ridgeline Discovery, a Versant Ventures Discovery Engine creates and operates Versant-financed innovative biotech companies in Basel, Switzerland.
In recent years, Ridgeline has assembled an international team of >
35 highly experienced drug discovery professionals and built and operated several new successful companies, including Black Diamond Therapeutics (Nasdaq : BDTX), Bright Peak Therapeutics and Monte Rosa Therapeutics.
Ridgeline is currently expanding its capabilities in Basel to support further company creation efforts in small molecules, biologics, and gene / cell therapy with focus on oncology and immunology.
This Basel (Switzerland) based position offers a tremendous opportunity to support our growing companies in an experienced, vibrant and agile biotech team.
The successful candidate will be highly motivated and enthusiastic with a positive can-do attitude, hands-on, strong analytical and organizational skills and strategic mindset.
Participate in the development of a GMP-compliant manufacturing process and control strategy for cell-based products (genetically engineered T-based and / or hematopoietic stem cell-based products)
Support design of studies and execute experiments needed to establish consistent manufacturing processes and analytic procedures for cellular products
Support evaluation and implementation of technologies and materials required for successful manufacturing cell therapy products
Participate in process characterization studies
Collaborate with research, analytical development, and external partners to design, develop and implement a GMP-compliant cell therapy manufacturing process
Review and / or assist in writing and revising technical documents including laboratory SOPs, protocols and reports
MS degree in bioengineering or life science or similar
Direct experience (2+ years) with manufacturing process development for mammalian cells or preferable primary cell cultures in a cell and gene therapy environment
Expertise with various cell culture platforms (e.g. cell culture bags, G-Rex and / or Cell culture stacks) and devices used in the manufacturing for cellular products (e.
g. CliniMACS Prodigy, CliniMACS plus, Sepax, and / or Lovo, etc.) would be desirable
Working knowledge with regard to the application of DoE approaches would be desirable
Experience with the cultivation of human cells is required, preferably primary T cells and / or hematopoietic stem cells
Experience within a GMP-regulated environment would be of advantage
Ability to work independently and to participate in cross-functional teams, meet deadlines, and organize and prioritize work
Self-organizer, keen attention to detail
Ability to acquire knowledge quickly in the rapidly expanding adoptive cell therapy field
Excellent communication skills with ability to communicate across a variety of audiences including team members and cross-functional project teams
To apply , please send us this application form together with your CV and Cover Letter .