PhD Position in Insect Chemical Ecology and Evolutionary Biology(4-year appointment)
University of Zurich
vor 5 Tg.

Your responsibilities

Plants produce a tremendous diversity of secondary metabolites as chemical defences against attack by diverse communities of herbivores.

In turn, herbivores may evolve resistance mechanisms to cope with these chemicals, allowing them to specialize on defended plants and escape competition from more generalist herbivores.

In evolutionary recent times, plants in the Brassicaceae genus Erysimum have gained the ability to produce novel toxic cardenolides, in addition to the ancestral glucosinolate defences of all Brassicaceae plants.

While several Brassicaceae-specialized herbivores can tolerate glucosinolate defences, there has been no confirmed case of specialized cardenolide resistance evolving in the Erysimum system to date.

The CARDEVOL project aims to make use of this evolutionary gain of a novel plant trait to elucidate the consequences of phytochemical diversification for plant-herbivore interactions.

As part of this PhD project, we will identify resistance mechanisms in insect herbivores towards novel chemical plant defences.

The successful candidate will work with a diverse set of insect herbivores from different feeding guilds and with varying degrees of host plant specialization.

The student will quantify current levels of tolerance to chemical defences in these herbivores, as generalized tolerance may serve as evolutionary stepping stones towards specialized resistance.

The student will also be involved in an experiment of natural selection that will attempt to evolve specialized herbivore resistance in real time.

Potential mechanisms of resistance will be identified through physiological experimentation, analysis of transcriptomic responses towards exposure to the novel defence, and transcriptomic and genomic analyses of evolving herbivore populations.

Your profile

The ideal candidate will have completed an MSc degree in Ecology, Entomology, or Molecular Biology, and has a strong track record of using molecular tools and methods to address fundamental questions in ecology and evolutionary biology.

Strong preference will be given to candidates with prior knowledge of transcriptomic and / or genomic methods and differential gene expression analysis.

Experience in working with insects and insect rearing is advantageous. Good knowledge of English in speaking and writing and familiarity with R (or another programming language) are expected.

What we offer

We offer varied and interesting work in an inspiring and socially relevant environment.

Diversity and inclusion are important to us.

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