Position Overview :
Genentech is seeking a Franchise Head, Clinical Development Global Head Hematology - NHL / CLLwith clinical and drug development experience to lead the NHL / CLL Hematology Global Franchise within our Hematology / Oncology Late Development organization.
This individual will be responsible for leadership, management, and strategic clinical oversight of the NHL / CLL Hematology Global Franchise.
The position will have significant accountability for setting strategy across these programs. The position will involve clinical development of novel agents targeting a number of diseases in the NHL / CLL Hematology setting.
In addition to managing a large global clinical development team, the Global Head of NHL / CLL Hematology Cancer will be responsible for providing guidance and oversight for the design, implementation, monitoring, analysis, and reporting of studies conducted for all NHL / CLL Hematology Cancer programs.
Context and Key Responsibilities :
This is a global role reporting to the Senior Vice President, Global Head of Clinical Development Oncology, Hematology. Member of the Product Development Hematology / Oncology Leadership Team (PDO LT) and cross-functional Joint Oncology Leadership Team (JOLT).
MD with Board Certification or eligibility in Hematology and clinical practice experience required as well as strong scientific competence demonstrated by peer reviewed publications or production of clinical expert reports.
Partner and Co-Lead the Hematology Franchise with the GPS (Global Product Strategy) lead for all funding decisions and priorities in NHL / CLL, and responsible for overarching strategy in NHL / CLL Hematology cancer.
Closely manage plans with all other therapeutic area franchises. Ensures GDLs and DLs (Global Development Leads and Development Leads) for each molecule manage their respective Development Working Groups with excellence and technical rigor.
Accountability to deliver late stage NHL / CL hematology clinical development plans, enabling regulatory submissions and approvals.
Noted disease area expert with credibility to interface with key external regulatory and healthcare organizations and stakeholders (i.
e. FDA, EMA, other Regulatory bodies, Payer organizations, Advisory Committees, Therapeutic Area Experts, and represent company for media, analysts).
Broadly represents the interests of Oncology and Hematology late development within Roche and Genentech, as a member of the Hematology Leadership Team, as well as through interactions with Research, Early Development, Medical Affairs, Commercial, Regulatory and Business Development senior leaders.
Contributes to the Late Stage Portfolio Committee (LSPC). Leads the strategic clinical oversight of the NHL / CLL Hematology late stage development portfolio with significant accountability for setting global strategy across these programs.
Ensures consistent and effective communication across all sites.
Accountable for building global working capability and establishing clear success metrics. Coach, manage and support employees to achieve business goals.
Actively manage talent and career development. Maintain and develop a positive organizational culture, by promoting the values of the focus on patients, science, and our people.
Prepare and manage resource and capacity, utilizing resources in the most efficient way. Determine and manage expenditures and budget within the NHL / CLL Hematology cancer late stage global franchise.
Key Accountabilities :
Broadly represent the interests of Hematology late development within Roche and GNE, as a member of the PDO LT, HLT, and JOLT, as well as through interactions with Research, Early Development, Medical Affairs, Commercial, Regulatory and Business Development senior leaders
Lead of the NHL / CLL Hematology Disease Area Team, co-chair with GPS franchise lead and accountable for strategic direction of disease area, priorities, budget and decision making
Closely interface with early development at Genentech and Roche to define opportunities to explore new areas of scientific discovery
Evaluate approved and late stage PDO molecules for new indication opportunities
Accountable for building global working capability and establishing clear success metrics
Noted disease expert with credibility to interface with key external health organizations (i.e. FDA, Advisory Committees, Key Opinion Leaders, media, analysts, WHO etc.)
Coach, manage and support employees to achieve business goals.
Actively manage talent and career development
Mentor and coach current and potential GDLs and DLs
Maintain and develop a positive organizational culture, by promoting the values of the focus on patients, science, and our people
Critical Experiences and Qualifications :
Candidates should have an M.D. or M.D. / Ph.D. with board certification / eligibility in Hematology; expertise in clinical drug development is required.
A minimum of 10 years drug development experience in a large biotech, pharmaceutical or clinical organization.
Clinical practice expertise in oncology and / or hematology.
Experience in Hematology cancers is preferred. Scientific experience in molecular oncology and / or oncology.
Significant preclinical / scientific research experience and publication record.
Proven experience interacting with senior and executive leadership.
Proven experience at filing products with global regulatory authorities (IND, BLA, and NDA). Required to travel internationally.
Technical / Functional Skill & Knowledge Areas :
Acts effectively as a substitute for the Senior Vice President or as a representative to other groups inside and outside of Roche / GNE for the relevant therapeutic area(s).
Demonstrated clinical trial experience (with significant clinical trial experience in the biotech or pharmaceutical industry).
Expert knowledge of Phase I-IV drug development.
Recognized as a subject matter expert within the field of Hematology or Oncology by both internal and external experts.
Experience leading and managing a large global scientific and medical group (comprised of direct and indirect reports) for complex high profile molecules and / or programs.
Proven strategic thinking and sound judgment.
Working knowledge of international regulatory environment.
Prepared to make decisions and take calculated risks, synthesizes detailed information, makes sound decisions based on risk assessment and balancing of priorities.
Ability to critically evaluate scientific data with a working knowledge of the Product Development long-range plan and experience with cross-functional departments.
Fluent in both verbal and written English with excellent presentation skills.
Demonstrated track record in leading and managing change on a large scale.
Leadership & Other Key Behaviors :
5+ years’ leadership experience.
Proven ability to effectively work in a global, cross-functional matrix organization.
Ability to work effectively in diverse cultures, showing aptitude in modifying style.
Successfully leverage external partnerships to achieve key objectives.
Proven ability to lead innovation and significant change.
Excellent strategic agility, willingness to experiment and take smart risks.
Demonstrated track record of leadership skills; has a proven track record in building mid to large-scale organizations and leading management and staff in such organizations to consistently meet or exceed their targets, goals and other objectives.
Outstanding partnership skills and a superior grasp of the overall business; previous track record includes identifying opportunities that have improved results in areas beyond direct management or influence.
Strong competitive awareness.
Outstanding organizational agility and interpersonal savvy : knows how to get things done
Who we are A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases.
Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity / expression, national origin / ancestry, age, mental / physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.