The PhD candidate will combine wet and dry lab expertise, use cutting-edge molecular and genetic approaches to identify novel therapeutic targets against Ewing sarcoma.
More specifically, this PhD project aims at :
1)Deciphering the molecular pathways driving these invasive / metastatic phenotypes using a spatial transcriptomics approach (Visium - 10x Genomics) in established 3D tumor models.
2)Implementing a new high throughput peptide screening approach to prevent metastasis in Ewing sarcoma.
What we offer
The laboratory has a strong expertise in genetic, epigenetic and preclinical approaches in sarcoma. We are a dynamic and growing team implementing cutting-edge research and developing tomorrow's treatments against pediatric, adolescent and young adult bone sarcomas.
You will work alongside other lab members and integrate the PhD Program in Cancer Biology of the University of Zürich. Salary for PhD students is set by the Swiss National Science Foundation (CHF 47'040.