Senior Scientist Mass Spectrometry Biologics Early Phase Development
TECHNICAL R & D GDD
Basel, Switzerland
vor 10 Tg.

Job Description

To develop our growing pipeline of products we are looking for a senior scientist in the area of mass spectrometry and analytical development.

The candidate will work in a team responsible for the characterization of therapeutic proteins of different formats by mass spectrometry.

Duties and Responsibilities :

  • Perform characterization of therapeutic proteins, protein-conjugates, and their posttranslational modifications by MS using state-of-the-art LC-MS equipment.
  • Compile analytical data from different analytical methods, write technical reports, and present conclusions in expert team meetings.
  • Develop new methodologies and improve processes for effective characterization of bio-therapeutics as well as automated data analysis.
  • Manage collaborations with external labs.
  • Ensure maintenance of specialized technical equipment and organization of the general lab infrastructure.
  • Effectively manage analytics characterization timelines to support several projects in parallel, and work closely with other teams in an international setting.
  • Provide technical training to team members as required.
  • Minimum requirements

  • BS / MS, PhD degree or equivalent in biochemistry, analytical chemistry or related field
  • At least 3 years of hands-on experience in mass spectrometric characterization of e.g. antibodies, bispecific Abs, therapeutic proteins.
  • Expert knowledge of state-of-the-art ESI-Q-TOF, Orbitrap and MALDI-TOF MS technologies as well as data processing software solutions.
  • Solid knowledge of protein chemistry and analytical methods for characterization of proteins (chromatography, electrophoresis, spectroscopy).

  • Ability to interpret and present scientific information critically and objectively.
  • Strong inter-personal skills ensuring close collaboration with multiple teams, communication with internal and external partners, and the ability to work in international teams.
  • Proficiency in English (oral and written) required, German of advantage.
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