Postdoctoral Researcher
University of Zurich
vor 3 Tg.

Your responsibilities

Our previous work has demonstrated a physical link between the disturbed metabolic pathway in methylmalonic aciduria and the Krebs (TCA) cycle.

Your project will use genetic (e.g. CRISPR-Cas) and pharmacological manipulation of involved enzymes, along with multi-omics technologies (e.

g. proteomics, metabolomics) and biochemical studies to investigate the interaction and inter-regulation of these pathways, in vitro and in cell models.

The goal is to identify potential entry points for nutritional complementation-based strategies, which can be translated further into animal models and the clinic.

Your profile

The highly motivated candidate will

  • have already obtained a PhD in biochemistry, molecular biology, or a related field
  • have a strong research track record
  • have prior experience with cellular models
  • The successful candidate will ideally

  • have experience with metabolically driven diseases (also incl. cancer, diabetes, etc)
  • have an interest in rare disease and clinical translation
  • be driven, goal- and team-oriented
  • What we offer

    We offer a competitive employment package, as well as a supportive and highly collaborative working environment that fosters academic career development.

    Zurich is a major European research hub that also offers an exceptionally high quality of life.

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