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Translational Medicine Leader (TML) (m/f)
F. Hoffmann-La Roche Ltd | Basel,Basel-Town,Switzerland, - il y a 1j
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The Translational Medicine Leader (TML) Oncology is a core member of the well-established Oncology Translational Medicine Group.

The TML leads the exploratory medicine strategy for early oncology drug assets. He/She is the key medical expert on the Global Project Team and ensures alignment of the development strategy with the overall Roche/GNE disease area strategy.

The TML owns and drives the exploration of clinical-translation data to design the clinical development strategy for new compounds (both small and large molecules).

The TML also shapes the hypotheses to be tested clinical experiments.The TML works with his/her Clinical Team and reports to the oDTA Group Head.

  • You are the medical lead and single point of contact for all medical questions in the exploratory phase of early oncology drug development (including Phase 2)
  • You lead the Clinical Expert Team (CET) and will represent the CET in the Global Project Team
  • You represent the main interface between Oncology Translational Medicine and (1) Oncology Discovery, (2) Clinical Operations, (3) Business, for project-related activities
  • You work closely with the Biomarker Experimental Medicine Leader to develop biomarker strategies
  • You support target and clinical candidate selection, be accountable for the design and the clinical and scientific content of experimental medicine studies to evaluate and validate targets
  • You propose, establish, assess and lead external collaborations to address strategic and tactical needs
  • You assure GCP, Clinical Operating Guidelines and Standard Operating Procedures are followed, be responsible for safety management (jointly with Drug Safety)
  • You support protocol development for experimental medicine and clinical pharmacology studies
  • You potentially have line management responsibility for clinical scientists and clinical science specialists
  • You be responsible for budget and manpower planning, performance management and personal development of reports
  • You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies.
  • Where a job title is not considered the final definition of who you are, but the starting point.

    You hold a MD with a minimum of 5 years clinical practice experience in Oncology/Hematology/Immunology. MD is mandatory.You have a mandatory minimum of 3 years experience in a pharmaceutical and/or biotech environment You have a proven record of scientific achievement with significant experience in drug development documented by presentations and publications in peer reviewed journalsYou have the ability to independently develop the clinical strategy for exploratory development You work as experienced matrix leader and decision maker with strong leadership skills to influence and motivate teams You have an understanding of contemporary translational research tools, including imaging, biomarkers and an understanding of unmet medical needs in oncology and ability to think beyond current paradigms of careYou have demonstrated early development expertise in oncology, e.g., you have served as Principal Investigator, have direct experience with early clinical development including protocol development, IND preparation, health authority interactions, etc.You have an analytical thinking and a high level of business awarenessYou have effective communication and presentation skills with different stakeholders in a matrix setting and the ability to influenceWe can trust in your excellent planning, organizational and leadership skills and you are fluent in English The preferred location for this position is Penzberg but can be located also in Basel, Zurich or New York.

    Please indicate your location of choice in your motivation letter.

  • Roche at Penzberg, near Munich, employees more than 5,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof.
  • From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.

    Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

    If you have a disability and need an accommodation in connection with the on-line application process, please email us at .


    The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant.

    However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)